Alzheimer’s Disease

The Link between Alzheimer’s Disease and Gum Disease

Pathogenic oral bacteria called Spirochetes may cause Alzheimer’s Disease. Spirochetes form plaques and curly fiberlike lesions in the brain. Their number progressively increases in patients with mild, moderate, and severe Alzheimer’s Disease. Spirochetes escape destruction of the host immune response and establish chronic infection and sustained inflammation.

Periodontal Disease is a chronic infection resulting from the interaction between pathogenic bacteria, like spirochetes, and the natural human host response. This interaction leads to localized (in the gums) and systemic (throughout the body) inflammation characterized by elevation of inflammatory molecules. Periodontal Disease through bacteria and/or inflammatory molecules may contribute to already elevated brain inflammatory molecules, therefore increasing risk of Alzheimer’s Disease.

FACT: Alzheimer’s Disease is the most common cause of dementia in older adults.